Matt, thanks. Some progress based on the tutorial. However:

Status: Resolving IP-Address for ftp.personalontologies.com
Status: Connecting to 64.22.82.198:21...
Status: Connection established, waiting for welcome message...
Response: 220---------- Welcome to Pure-FTPd [TLS] ----------
Response: 220-You are user number 1 of 50 allowed.
Response: 220-Local time is now 07:50. Server port: 21.
Response: 220-This is a private system - No anonymous login
Response: 220 You will be disconnected after 15 minutes of inactivity.
Command: AUTH TLS
Response: 234 AUTH TLS OK.
Status: Initializing TLS...
Command: USER personal
Status: Verifying certificate...
Status: TLS/SSL connection established.
Response: 331 User personal OK. Password required
Command: PASS ********
Response: 530 Login authentication failed
Error: Could not connect to server
Current settings in FileZilla (which when I get them right I'll send back for everyone):
Host ftp.mydomain.com
Port blank
Servertype FTPES - FTP over explicit TLS/SSL
Logontype Normal
User my cPanel username
Password my cPanel password
Transfer Setting passive
I also had to say at one point that I approved a certifcate.

Look forward to advice.

Thanks,

John